ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate

ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate - Names and Identifiers

Name	ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate
Synonyms	ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate
CAS	854778-10-2

ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate - Physico-chemical Properties

Molecular Formula	C11H9F2NO2
Molar Mass	225.1914664
Storage Condition	2-8°C

ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate - Introduction

ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate is an organic compound with the chemical formula C11H7F2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate is a colorless to light yellow liquid.
2. Solubility: it can be dissolved in organic solvents such as ethanol, ether and dichloromethane, but not soluble in water.
3. Melting point and boiling point: its melting point is -25 ℃, boiling point is 172-174 ℃.
4. Density: its density is 1.25 g/cm.

Use:
ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate has a wide range of applications in the field of organic synthesis, and is often used as an intermediate or starting material. Specific uses include:
1. For the preparation of drugs, pesticides and dyes and other chemicals.
2. Used as catalyst and reaction intermediate in organic synthesis.
3. Used as a surfactant or additive.

Method:
The preparation of ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate can be achieved by the following steps:
1. First, Phenyl Ketone is converted to Phenyl Vinyl cyanide (vinylbromide) by cyanation reaction.
2. Phenylvinyl cyanide is then reacted with ethyl difluoroformate to give ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate.

Safety Information:
When handling ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate, the following safety measures need to be observed:
1. Should wear protective gloves, protective glasses and protective mask and other personal protective equipment.
2. Avoid contact with skin, eyes and clothing. In case of contact, rinse immediately with plenty of water.
3. Maintain a well-ventilated working environment.
4. Store in a cool, dry place, away from fire and oxidant.

This information is very important for users to process and use ethyl 2-(4-cyanophenyl)-2,2-difluoroacetate more safely.

Last Update：2024-04-09 21:01:54